Published: 2016-12-28

Prescription pattern in indoor patients of cardiovascular diseases: a descriptive study in a tertiary care hospital attached to a government medical college

Pravin S. Rathod, Praveenkumar T. Patil, Rekha P. Lohar, A. W. Patil


Background: In India, one of the leading causes of death is cardiovascular diseases (CVDs). The study of prescription pattern ensures rational pharmacotherapy and assures quality medical care to the patients. Hence the present study was conducted to observe the prescription pattern of drugs among the indoor patients of cardiovascular diseases in a tertiary care hospital attached to a Government Medical college.

Methods: A retrospective observational study of 9 month duration was undertaken from January- September 2015. A total number of 113 indoor cardiovascular disease patients’ case sheets were utilized for our study from medicine and ICCU department of a tertiary care hospital. The data was analysed and the results were expressed as counts and percentage.

Results: Of 113 patients, most of the patients were of the age group of 56-65 years (40.71%). The prevalence of CVDs was higher in females (56.64%) than males (43.36%). Hypertension (58.41%) and Ischemic heart disease (41.59%) were found to be predominant CVDs. Nifedipine (53.10%), Atenolol (31.86%), Isosorbide dinitrate (40.71%), Atorvastatin (53.10%) were the most commonly prescribed cardiovascular drugs. Aspirin and Clopidogrel combination was prescribed in 46.90% of CVD patients. The average number of drugs per prescription was 6.53.

Conclusions: The present study shows that most of drugs were prescribed rationally according to the current treatment guidelines except the under use of ACEIs and ARBs in hypertensive diabetes mellitus patients. Standard treatment guidelines should be circulated among practicing physicians to encourage rational prescription.


Cardiovascular diseases, Prescription Pattern, Indoor patients, Hypertension, Ischemic heart disease

Full Text:



Muhit MA, Rahman MO, Raihan SZ, Asaduzzaman M, Akbar MA, Sharmin N. Cardiovascular disease prevalence and prescription patterns at a tertiary level hospital in Bangladesh. Journal of Applied Pharmaceutical Science. 2012;2:80-4.

Gaziano TA, Gaziano JM. Epidemiology of Cardiovascular Disease. In Lango DL, Harrison’s Principles of Internal Medicine, 18th edition. New york, Mc Graw Hill. 2012:1811-1816.

Shastry R, Bethi Y, Kumar JU. Trends in drug usage among elderly with cardiovascular diseases. Int J Basic Clin Pharmacol. 2014;3:723-5.

Shankar R, Partha P, Shenoy N. Prescribing patterns of drugs among patients admitted with cardiovascular disorders in the internal medicine ward: prescribing patterns in inpatients. Internet J Pharmacol. 2001;1(2).

Srishyla MV, Krishnamurthy M, Nagarani MA, Andrade C, Venkataraman BV. Prescription audit in an Indian Hospital setting using the DDD concept. Ind J Pharmacol. 1994;26:23-8.

Ramsay LE. Bridging the gap between clinical pharmacology and rational drug prescribing. Br J Clin Pharmacol. 1993;35:575-6.

Vries MD, Heluling RH, Hogerzeil HV, Freste DA. Guide to good prescribing. A practical guide W.H.O. 1994.

Patil SB, Raikar SR, Patil S, Raikar DR. Prescription pattern of cardiovascular drugs in intensive cardiac care unit patients in a tertiary care hospital. Int J Basic Clin Pharmacol. 2015;4:1100-3.

Ghosh A, Bhagat M. Anthropometric and body composition characteristics in pre- and postmenopausal Asian Indian women: Santiniketan women study. Anthropol Anz. 2010;68:1-10.

Loscalzo J. Approach to the patient with possible cardiovascular Disease. In Lango DL, Harrison’s Principles of Internal Medicine, 18th edition. New york, Mc Graw Hill. 2012:1817-20.

Zafar F, Ali H, Naveed S, Korai OU, Rizvi M. (2015) Drug Utilization Pattern in Cardiovascular Diseases: A Descriptive Study in Tertiary Care Settings in Pakistan. J Bioequiv Availab. 2015;7:059-62.

Nagabushan H, Roopadevi HS, Prakash GM, Pankaja R. A prospective study of drug utilization pattern in cardiac intensive care unit at a tertiary care teaching hospital. Int J Basic Clin Pharmacol. 2015;4:579-83.

Christian RP, Rana DA, Malhotra SD, Patel VJ. Evaluation of rationality in prescribing, adherence to treatment guidelines, and direct cost of treatment in intensive cardiac care unit: a prospective observational study. Indian J Crit Care Med. 2014;18(5):278-84.

Datta S, Udupa AL. Antihypertensive drug use in patients having comorbid diabetes: Cross sectional prescription pattern study in a tertiary care hospital. Asian Journal of pharmaceutical and clinical research. 2010;3:43-5.

Tasneem S, Fouzia N. Drug utilization study in ischemic heart diseases associated with diabetes and hypertension. Int J Pharm Bio Sci. 2010;1(3):1-4.

Tripathi KD. Drug affecting coagulation, bleeding and thrombosis. In: Tripathi KD, editor. Text Book of Essentials of Medical Pharmacology. 7th Edition, New Delhi, Jaypee Brother Medical Publication. 2013:613-633.