DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20173273

Implementing standardised rhodes index to measure the efficacy of ginger extract (Zingiber officinale) in pregnancy induced nausea and vomiting

Asha P. Dass, Priyadarshini Deodurg, Sandhiya Rajappan

Abstract


Background: Although nausea and vomiting are natural signs of pregnancy affecting about half the pregnant women during their first trimester of pregnancy, it is unpleasant and difficult symptom to deal with. Considering the fact that medication during pregnancy is not advised, we decided to study the efficacy of a natural product to control nausea and vomiting during early pregnancy. Our study was directed to estimate the efficacy of ginger extract (Zingiber officinale) in pregnancy induced nausea and vomiting.

Methods: A total of 30 women with pregnancy of 4-16 weeks, suffering from nausea and vomiting were included in this study (n=30). Subjects were given ginger extract 250mg, to be taken 3 times a day half an hour before food for 1 week. Severity of vomiting was assessed by Rhodes Index of Nausea and Vomiting by the patients. Baseline scores were compared with the score at the end of 7 day. The findings were analysed statistically.

Results: Effect with the ginger extract in pregnancy induced nausea and vomiting was assessed at the end of treatment (day 7) and compared with the baseline values. Four patients reported symptoms of heartburn. Otherwise, there were no other reports of any adverse effects. The results showed significance (p <0.005).

Conclusions: Ginger extract (Zingiber officinale) helps in reducing severity and frequency of pregnancy induced nausea and vomiting. Therefore, we conclude that ginger extract can be used for mild to moderate nausea and vomiting induced by pregnancy during first trimester.


Keywords


Ginger extract, Pregnancy induced nausea and vomiting, Rhodes Index, Zingiber officinale

Full Text:

PDF

References


Miller F. Nausea and vomiting in pregnancy: the problem of perception is it really a disease?. American Journal of Obstetrics and Gynecology 2002; 186(5):S182-3.

Woolhouse M. Complementary medicine for pregnancy complications. Australian Family Physician. 2007;35(9):695.

Lacasse A, Rey E, Ferreira E, Morin C, Berard A. Validity of a modified Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scoring index to assess severity of nausea and vomiting of pregnancy. American Journal of Obstetrics and Gynecology. 2008;198(1):71.e1-71.e7.

O'Brien B, Relyea MJ, Taerum T. Efficacy of P6 acupressure in the treatment of nausea and vomiting during pregnancy. American Journal of Obstetrics and Gynecology. 1996;174(2):708-15.

Zhou Q, O'Brien B, Soeken K. Rhodes Index of Nausea and Vomiting--Form 2 in pregnant women. A confirmatory factor analysis. Nursing Research. 2001;50(4):251-7.

Zhou Q, O'Brien B, Soeken K. Rhodes Index of Nausea and Vomiting--Form 2 in pregnant women. A confirmatory factor analysis. Nursing Research. 2001;50(4):251-7.

Jewell D. Nausea and vomiting in early pregnancy. American Family Physician. 2003;68(1):143-4.

Eliakim R, Abulafia O, Sherer DM. Hyperemesis gravidarum: a current review. American Journal of Perinatology. 2000;17(4):207-18.

Kousen M. Treatment of nausea and vomiting in pregnancy. American Family Physician. 1993;48(7):1279.

Quinlan JD, Hill DA. Nausea and vomiting of pregnancy. American Family Physician. 2003;68(1):121-8.

Swallow BL, Lindow SW, Masson EA, Hay DM. Development of an instrument to measure nausea and vomiting in pregnancy. Journal of Obstetrics and Gynaecology. 2002;22(5):481-5.

Bsat FA, Hoffman DE, Seubert DE. Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. Journal of Perinatology. 2003;23(7):531.

Koch KL. Gastrointestinal factors in nausea and vomiting of pregnancy. American Journal of Obstetrics and Gynecology. 2002;186(5):S198-203.

Vutyavanich T, Kraisarin T, Ruangsri R. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. Obstet Gynecol. 2001 Apr;97(4):577-82.

Keating A, Chez RA. Ginger syrup as an antiemetic in early pregnancy. Altern Ther Health Med. 2002 Sep-Oct;8(5):89-91.

Ozgoli G, Goli M, Simbar M. Effects of ginger capsules on pregnancy, nausea, and vomiting. J Altern Complement Med. 2009 Mar;15(3):243-6.

Willetts KE, Ekangaki A, Eden JA. Effect of a ginger extract on pregnancy-induced nausea: a randomised controlled trial. Aust N Z J Obstet Gynaecol. 2003 Apr;43(2):139-44.

Ding M, Leach M, Bradley H. The effectiveness and safety of ginger for pregnancy-induced nausea and vomiting: a systematic review. Women Birth. 2013 Mar;26(1):e26-30.

Rhodes VA, Watson PM, Johnson MH. Development of a reliable and valid measure for nausea and vomiting. Cancer Nurs. 1984;7:33-41.