Buprenorphine/naloxone maintenance therapy in patients with meperidine use disorder


  • Ahmet Bulent Yazici Department of Psychiatry, Sakarya University, Training and Research Hospital, Sakarya, Turkey
  • Alime Burcin Saykan Department of Psychiatry, Sakarya University, Training and Research Hospital, Sakarya, Turkey
  • Esra Yazici Department of Psychiatry, Sakarya University, Training and Research Hospital, Sakarya, Turkey
  • Atila Erol Department of Psychiatry, Sakarya University, Training and Research Hospital, Sakarya, Turkey




Addiction, Buprenorphine, Meperidine, Naloxone, Remission


Meperidine hydrochloride is a synthetic opioid and a weak µ receptor agonist. Meperidine use disorder is mostly iatrogenic and is common in health care workers. In addition, it is prescribed in acute and chronic pain complaints, and has a high potential for creating addiction. Treatment of meperidine use disorder is a challenging issue and there is no standardised treatment for meperidine addiction. Buprenorphine is a μ receptor partial agonist, a long-acting synthetic opioid for the treatment of opioid dependence and has a buprenorphine/naloxone (BN) form combined with naloxone. Buprenorphine maintenance therapy is one of the treatment options performed in opiate use disorder. But there is a paucity of data about treatment of meperidine use disorder. Here, a full remission case report is presented with BN maintenance treatment for a patient with meperidine use disorder diagnosis.


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How to Cite

Yazici, A. B., Saykan, A. B., Yazici, E., & Erol, A. (2017). Buprenorphine/naloxone maintenance therapy in patients with meperidine use disorder. International Journal of Basic & Clinical Pharmacology, 6(9), 2292–2295. https://doi.org/10.18203/2319-2003.ijbcp20173762



Case Reports