DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20172751

Cost variation analysis of oral anti-diabetic agents available in drug store of the tertiary care hospital and in Indian market

Aparna Chincholkar, Ganesh Pentewar

Abstract


Background: Diabetes, a chronic disorder and requires life-long treatment. Cost of drug treatment is a major hurdle related to medication compliance in Type 2 Diabetes Mellitus. The objective of the study was to find out the cost of antidiabetic drugs available in the drug store of a tertiary care hospital and compare it with the different brands of the same drugs available in Indian market. To evaluate the difference in cost of different brands of same active drug by calculating percentage variation of cost.

Methods: Cost of single compound and combination compound oral antidiabetic drugs available in drug store and those same drugs in Indian market manufactured by different companies, in the same strength, number and dosage form. The percentage price variation between minimum and maximum cost of drugs were calculated. The percentage difference in cost of antidiabetic drugs available in drug store and in the Indian market was calculated.

Results: The percentage price variation of oral antidiabetic drugs available in drug store was found to be as follows. In sulfonylureas, it was highest in Glimepiride (2mg) 1962, 96%, among biguindes, Metformin (500mg) 3012.5%, among alpha glucosidase inhibitors Voglibose (0.2mg) 387.17%. Voglibose (0.3mg) 361.30%. Among combination therapy Voglibose (0.3mg) + Metformin (500mg) 2809% showed maximum price variation.

Conclusions: The average percentage price variation of different brands of the same drug is very wide and hence the physician must keep this in mind while prescribing since the drug treatment of type II diabetes mellitus is usually lifelong. Hence, manufacturing companies should aim to decrease the price variation while maintaining the therapeutic efficacy. Drug store of tertiary care hospital should try to provide the oral antidiabetic drug with least cost and sell the generic drugs.


Keywords


Brands, Diabetes mellitus, Drug store, Manufacturing companies, Oral antidiabetic drugs, Price variation

Full Text:

PDF

References


Rao NVR, Chowdary BM, Mergaret TM. Cost analysis study of oral anti-diabetic drugs Available in Indian Govt generic (JAN AUSHADHI, JEEVANDHARA) drugs and brand drugs market in rural/ urban area of Guntur, Andhrapradesh, India. World J of Phar Res. 2015;4(5):2201-10.

Jana S, Mondal P. Pharmacoeconomics: The need to sensitize undergraduate medical students. Indian Pharmacol. 2005;37:277-8.

Jha NJ. Cost Analysis for Management of Type-2 Diabetes: A Case Study of Rural and Urban Setting. Journal of Nepal Health Research Council. October 2004;2(2):55-9.

Phatak AM, Hotwani JH, Deshmukh KR, Panchal SS, Naik MS. Cost analysis of long established and newer oral antiepileptic drugs available in the Indian market. Int J Med Res Health Sci. 2015;4(4):744-8.

Hussain S, Pharm M. Cost variation analysis of Oral Hypoglycaemic agents available in Indian market: An Economic Perspective. International Journal of Pharma Sciences and Research (IJPSR). 2015;6(5):913-8.

Prices of brand drugs, Medguideindia. Available at: http://www.medguideindia.com/show_brand.php

Jadhav NB, Bhosale MS, Adhav CV. Cost analysis study of oral antidiabetic drugs available in Indian market. Int J Med Res Health Sci. 2013;2(1):63-9.

Binaya S. Cost analysis of oral hypoglycemic agents available in Nepalese market. MJSBH. 2014;13(2):6-9.

Tiwari A, Yadav P. pharmacoeconomic study of antidiabetic drugs. Proceedings of 27th IRF International Conference, 24th May 2015, Pune, India, ISBN: 978-93-85465-17-8 36.

Misra B, Jain SK, Mehta Y. A study on availability and prices of medicines in India. National Pharmaceutical Pricing Authority; 2002. Available at: http://nppaindia.nic.in/index1.html

Sarkar PK. A rational drug policy. Indian J Med Ethics. 2004;1(1):11-2.

Roy V, Rewari S. Ambiguous drug pricing: a physician’s dilemma. Indian J Pharmacol. 1998;30(6):404-7.

Wertheimer AI, Grumer SK. Overview of international pharmacy pricing. Pharmacoeconomics. 1992 Dec 1;2(6):449-55.