Pramipexole with leuprolide: a treatment strategy for PGAD


  • Rajnish Raj Department of Psychiatry, Government Medical College, Patiala, Punjab, India
  • Nisha Bhagat Department of Obstetrics and Gynecology, Government Medical College, Patiala, Punjab, India



Impulse-control disorder not otherwise specific, Leuprolide, Non-paraphilic sexual addiction, Persistent genital arousal disorder, Restless genital syndrome


Persistent genital arousal disorder (PGAD) is described as the spontaneous, intrusive, and unwanted genital arousal in the absence of sexual interest and desire. Whether, its etiology is central or peripheral neurovascular in nature, it is still unclear. However, patient presents with symptoms of persistent engorgement of genital erectile and vascular tissue. The majority of women report PGAD as distressing. The symptoms usually occur in females in the age group 25-58 years especially in perimenopausal phase. The case is reported of PGAD in 19-year old female who was treated successfully with Pramipexole and Leuprolide.


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How to Cite

Raj, R., & Bhagat, N. (2017). Pramipexole with leuprolide: a treatment strategy for PGAD. International Journal of Basic & Clinical Pharmacology, 6(7), 1828–1832.



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