Drug utilization pattern of analgesics as a teaching tool for rational therapy to MBBS students in a medical college at Dehradun, Uttarakhand, India
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20171089Keywords:
Analgesics, Drug Utilization, Rational prescribingAbstract
Background: As a need to introduce Clinical Pharmacology at the undergraduate level the drug utilization studies (DUS) offer useful methods for teaching and training in drug therapy. The indiscriminate use of medicines results in unwanted side effects, drug interactions. Thus keeping this view in mind, this drug utilization research was set to evaluate the prescribing pattern of analgesics to impart certain basic skills to MBBS students which will form an integral component of practicing rational therapeutics.
Methods: The retrospective study was conducted by Pharmacology department in SGRRIM and HS. A total of 726 prescriptions were collected by 2nd professional MBBS students entering 5th semester and randomly evaluated for prescribing pattern using WHO drug use indicators.
Results: A total of 726 prescriptions were analyzed. Male:Female ratio was 470:256(1.8:1). Age wise distribution of patients 0-15years 122(16.80%), 16-30 years 139(19.41%), 31-45years 242 (33.33%), 46-60 years 113(15.56%) and >60years 110 (15.15%). A total of 4663 drugs were prescribed. 435(9.32%) were analgesics. 208 (47.81%) Paracetamol, 66 (15.17%) Tramadol, 62(14.25%) Aceclofenac, 51 (11.72%) Diclofenac, 46 (10.57%) Ibuprofen and 2(0.45%) Buprenorphine were prescribed. 301 (69.20%) Oral drugs and 134 (30.80%) Injectable were prescribed. 108 (24.83%) Numbers of Fixed dose combinations. 0.60 of analgesics were prescribed per prescription. 381 (87.59%) analgesics were prescribed from National Essential Medicine list 2015. 369 (84.83%) drugs were prescribed by brand names.
Conclusions: The main purpose of undergraduate medical curriculum is to develop the requisite diagnostic and therapeutic skills of a basic doctor. Such type of drug utilization studies is set with the objective to encourage rational prescribing, and to identify good and bad prescribing practices.
References
Rahman S, Begum ZA, Samad K. Prescribing pattern of nonsteroidal antiinflammatory drugs at outpatient departments of teaching hospital. Bangladesh J Pharmacol. 2007;2:1-6.
Bader P, Echtle D, Fonteyne V, Livadas K, De Meerleer G, Paez Borda A, et al. Guidelines on Pain Management. European Association of Urology. 2010:7-11.
Sen S, Bathini P. Auditing analgesic use in post operative sitting in a teaching hospital. J of Cli Dia Res. 2015;9(4):FC01-04.
Bawazir SA. Prescribing pattern at community pharmacies in Saudi Arabia. International Pharmacy Journal. 1992;6:5.
Mohammed TCH, Beegum IM, Perumal P. Prescribing pattern of analgesics in a tertiary care hospital. International journal of pharma tech and research. 2011;3:1521-9.
Vlahovic-Palcevski V, Wettermark B, Bergman U. Quality of nonsteroidal anti-inflammatory drug prescribing in Croatia (Rijeka) and Sweden (Stockholm). Eur J Clin Pharmacol. 2002;58:209-14.
Paul AD, Chauhan CK. Study of usage pattern of nonsteroidal anti-inflammatory drugs (NSAIDs) among different practice categories in Indian clinical setting. European J Clin Pharmacol. 2005;60:889-92.
Henry D, Lim LL, Garcia Rodriguez LA, Perez Gutthann S, Carson JL, Griffin M. Variability in risk of gastrointestinal complications with individual nonsteroidal anti-inflammatory drugs: results of a collaborative meta-analysis. British Medical Journal. 1996;312:1563-6.
Builders MI, Okonta JM, Aguwa CN. Prescribing patterns of analgesics in a community hospital in Nsukka. J Pharm Sci and Res. 2011;3(12):1593-8.
WHO. The selection of essential drugs, technical support series no.-615, report of a WHO Expert committee. Geneva; WHO;1977.
Shalini S, Ravichandran V, Mohanty BK, Dhanraj SK, Saraswati R. Drug utilization studies an overview. International Journal of Pharmaceutical Sciences and Nanotechnology. 2010;3(1):803-10.
Pradhan SC, Shewade DG, Shashindran CH, Bapna JS. Drug utilization studies. The National Medical Journal of India. 1998;1(4):185-9.
