An observational cross-sectional study to assess knowledge, attitude and practice of resident doctors and nursing professionals regarding pharmacovigilance in a tertiary care teaching hospital in Central India
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20171676Keywords:
Attitude and practice, Knowledge, Nursing professionals, Pharmacovigilance, Resident doctorsAbstract
Background: Adequate knowledge, positive attitude and motivated practice of pharmacovigilance are the building pillars of ADR reporting. This study was conducted to evaluate the knowledge and attitude towards pharmacovigilance and adverse drug reaction reporting among the resident doctors and nursing staff in AIIMS Bhopal, Madhya Pradesh, India.
Methods: This cross-sectional questionnaire based study was carried out in a tertiary care centre. The survey was carried out using a pre-validated questionnaire that included 20 questions to evaluate the participant’s knowledge, attitude and practice.
Results: Answers to knowledge based questions were given correctly by around 82.6% (95% CI 0.7576 to 0.8794) of resident doctors and 74% (95% CI 0.6033 to 0.8424) nursing professionals. The difference of basic knowledge about pharmacovigilance between resident doctors and nursing professionals was insignificant (p-value is 0.7967). The most common reason for underreporting was unawareness, which was opted by 69% (95% CI 0.6153-0.7617) of resident doctors, while among the 58% (95% CI 0.4422-0.7064) nursing staff, the major factor was non-feasible ADR monitoring system in hospital. The suggestion of conducting training and awareness programme to promote ADR reporting given by resident doctors and nursing staff were 85% (95% CI 0.7872-0.0957) and 80% (95 % CI 0.6677-0.8895) respectively.
Conclusions: The participants were well aware of pharmacovigilance and adverse drug reaction reporting. They had expressed the positive attitude towards pharmacovigilance and ADR reporting. But the routine practice of reporting ADRs is lacking. Hence there is need for increasing awareness and building positive attitude and practices among the health care professionals.
References
Desai CK, Iyer G, Panchal J, Shah S, Dikshit RK. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspect Clin Res. 2011;2:129-36.
World Health Organization. Safety of medicines. A guide to detecting and reporting adverse drug reactions. Geneva, Switzerland: World Health Organization; 2002.
Bouvy JC, De Bruin ML, Koopmanschap MA. Epidemiology of adverse drug reactions in Europe: a review of recent observational studies. Drug Saf. 2015;38:437-53.
Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients. A meta-analysis of prospective studies. JAMA. 1998;279:1200-5.
Ramesh M, Pandit J, Parthasarathi G. Adverse drug reactions in a south Indian hospital-their severity and cost involved. Pharmacoepidemiol Drug Saf. 2003;12:687-92.
Classen DC, Pestotnik SL, Evans RS, Lloyd JF, Burke JP. Adverse drug events in hospitalize patients. excess length of stay, extra costs and attributed mortality. JAMA. 1997;277:301-6.
McDonnell PJ, Jacobs MR. Hospital admissions resulting from preventable adverse drug reactions. Ann Pharmacother. 2002:36;1331-6.
Feely J, Moriarty S, O'Connor P. Stimulating reporting of adverse drug reactions by using a fee. BMJ. 1990;300:223.
Lopez-Gonzalez E, Herdeiro MT, Figueiras A. Determinants of under-reporting of adverse drug reactions: a systematic review. Drug Saf. 2009;32:19-31.
Hardeep, Bajaj JK, Kumar R. A survey on the knowledge, attitude and the practice of pharmacovigilance among the health care professionals in a teaching hospital in Northern India. J Clin Diag Res. 2013;7(1):97-9.
Qing L, Su-min Z, Hua-ting C, Shi-ping F, Xin Y, Dong L. The awareness and the attitudes of the healthcare professionals in China about/towards the reporting of adverse drug reactions. Chinese Med J. 2004;117(6):856-61.
Ekman E, Bäckström M. Attitude among hospital physicians to the reporting of adverse drug reactions in Sweden. Euro J Clin Pharmacol. 2009;65(1):436.
Bateman DN, Sanders GLS, Rawlins MD. The attitudes to the adverse drug reaction reporting in the northern region. Br J Clin Pharmacol. 1992;34(5):421-6.
Vallano A, Pedrós C, Agustí A, Cereza G, Danés I. Educational sessions in pharmacovigilance: What do the doctors think? BMC Res Notes. 2010;3:311.
Oshikoya K, Awobusuyi J. Perception of doctors to adverse drug reactions in a teaching hospital in Lagos, Nigeria. BMC Clin pharmacol. 2009;9:14.
Pimpalkhute SA, Jaiswal KM, Sontakke SD, Bajait CS, Gaikwad A. Evaluation of awareness about pharmacovigilance and adverse drug reaction monitoring in resident doctors of tertiary care teaching hospital. Indian J Med Sci. 2012;66:55-61.
Jha N, Rathore DS, Shankar PR, Gyawali S, Alshakka M, Bhandary S. An educational intervention’s effect on healthcare professionals’ attitudes towards pharmacovigilance. AMJ. 2014;7(12):478-89.
Tabali M, Jeschke E, Bockelbrink A, Witt CM, Willich SN, T, Matthes H. An educational intervention to improve the physicians’ reporting of the adverse drug reactions (ADRs) in a primary care set- ting in the complementary and alternative medicine programs. BMC Public Health. 2009;9:274.
Figueiras A, Herdeiro MT, Polonia J, Gestal-Otero JJ. An educational intervention to improve physician reporting of adverse drug reactions: a cluster randomized controlled trial. JAMA. 2006;296:108693.
