An open labeled study to evaluate efficacy and safety of ampucare in patients with bedsore


  • Janardhan Singh Department of Pharmacology,PGIMS, Rohtak-124001, India
  • Sukhbir Singh Sangwan Orthopedic Surgery, PGIMS, Rohtak-124001, India
  • Jarnail Singh Department of Pharmacology,PGIMS, Rohtak-124001, India
  • Ram Chandar Siwach Orthopedic Surgery, PGIMS, Rohtak-124001, India
  • Govind Shukla SBMN Ayurvedic College, Rohtak, India


Ampucare, Bedsore, Povidone iodine, Wound healing


Background: To evaluate efficacy and safety of ampucare, a polyherbal product, in patients with bedsore.

Methods: One hundred patients, either sex, more than 18 years of age, with bedsore were divided in to two groups of 50 each. Group-I- Served as control- povidone iodine solution was applied locally on the bedsore, once daily. Group- II- Treatment group- ampucare lotion was applied locally, once daily. Primary end point was time to wound healing and secondary end point included reduction in wound surface area at day-7 and at treatment completion. Percent patients cured, improved, or treatment failure were noted. Depth of wound, % healing and adverse effects were recorded.

Results: Application of ampucare in patients with bedsore resulted in rapid healing as compared to control group. Reduction in wound surface area was significant (p<0.01) in group-II. Maximum gain in thickness of granular tissue was observed in this group. In treatment group 68% patients showed excellent response as compared to 60 % in control group. Ampucare was well tolerated.

Conclusions: Ampucare treatment markedly accelerates wound healing in patients with bedsore.


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How to Cite

Singh, J., Sangwan, S. S., Singh, J., Siwach, R. C., & Shukla, G. (2017). An open labeled study to evaluate efficacy and safety of ampucare in patients with bedsore. International Journal of Basic & Clinical Pharmacology, 2(4), 371–374. Retrieved from



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