Metformin induced yellow nails: a rare entity


  • Tarun Sharma Department of Medicine, Civil Hospital Kangra, Himachal Pradesh, India
  • Aradhna Sharma Department of Pharmacology, Dr. RPGMC Kangra, Tanda, Himachal Pradesh, India
  • Mukul Bhatnagar Department of Cardiology, Dr. RPGMC Kangra, Tanda, Himachal Pradesh, India



Adverse drug reaction, Metformin, Yellow nails


This article reports an interesting and a rare case of metformin induced nail disorder in a middle aged female with type 2 diabetes. The patient had been receiving metformin one 1500mg daily from the last 6 months and noticed her finger nails gradually thickened and turned yellow. On stopping the metformin, the nails gradually normalized. The patient was treated further with glimepiride and insulin glargine. After 3 months of discontinuation of metformin there was a significant improvement in the nails. Clinicians should be aware of metformin induced yellow discolouration of nails, though a curable and reversible condition if diagnosed well in time.


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How to Cite

Sharma, T., Sharma, A., & Bhatnagar, M. (2017). Metformin induced yellow nails: a rare entity. International Journal of Basic & Clinical Pharmacology, 6(2), 469–470.



Case Reports