DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20151597

Compliance to prescribed medication among patients in a tertiary care hospital using Morisky-Green test

Megaravalli R. Manasa, Josephine Kennedy Preethy, Idoor D. Sachin

Abstract


Background: Compliance to medication is an important factor in the success of any treatment. It also reduces the health care cost. The objective of the study was to examine compliance of patients to treatment and investigate reasons for such compliance and to quantify non adherence to medications and raise awareness about such factors.

Methods: A prospective cross sectional questionnaire based study was conducted in 300 patients during three month period in 2013. The inclusion criteria was patients aged >18 years of both sexes and on treatment for diseases like asthma, hypertension, diabetes and coronary artery disease. Compliance was assessed using Morisky-Green test. Data was analysed by SPSS 19 and Chi square test was used to analyse the contingency tables and P ≤ 0.05 was considered significant.

Results: The study revealed a compliance of 40.7%. There was statistically significant association between compliance and younger age, lower level of education, low socio-economic status, acute disease and presence of comorbidity. The common causes for non-compliance were forgetfulness and side effects of drugs.

Conclusions: More than half of the study subjects were non-compliant. Hence a conscious effort is needed to educate the patients regarding their disease and the importance of compliance to treatment.


Keywords


Compliance, Medication, Morisky-Green test

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References


WHO, 2003. Adherence to long-term therapies: evidence for action. Geneva: World Health Organization. ISBN 92-4-154599-2.

Al-banna HI, Moha SMS. Compliance to Antihypertensive Treatment and Causes of Partial or Poor Compliance in Patients Attending Ali-Kamal Consultation Center in Suliamania. Zanco J. Med. Sci. 2010;14(Special issue 1):78-84.

Al-Dabbagh SA, Aswad SM. Compliance of Hypertensive Patients to Management in Duhok Governorate Using Morisky-Green Test. Duhok Med J. 2010;4(1):28-39.

Clark LT. Improving compliance and increasing control of hypertension: Needs of special hypertensive populations. Am Heart J. 1991;121(2):664-9.

Al-Sowielem LS, Elzubier A. Compliance and knowledge of hypertensive patients attending PHC centres in Al-Khobar, Saudi Arabia. East Mediterr Health J. 1998;4(2):301-7.

Santhanakrishnan I, Lakshminarayanan S, Kar SS. Factors affecting compliance to management of diabetes in Urban Health Center of a ter! tiary care teaching hospital of south India. J Nat Sc Biol Med. 2014;5:365-8.

Nuesch R, Schroeder K, Dieterle T, Martina B, Battegay E. Relation between insufficient response to antihypertensive treatment and poor compliance with treatment: A prospective case-control study. BMJ. 2001;323:142-6.

Constantini L. Compliance, adherence, and self-management: Is a paradigm shift possible for chronic kidney disease clients? CANNT J. 2006;16:4:22-6.

Acharya JP, Acharya I. Sociodemographic factors influencing compliance of medication in an urban OPD setting. J Sci Soc. 2014;41:101-7.

Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24(1):67-74.

Strelec MA, Mion Jr AM. The influence of patient's consciousness regarding high blood pressure and patient's attitude in face of disease controlling medicine intake. Arq Bras Cardiol. 2003;81(4):349-54.

Linn MW, Linn BS, Stein SR. Satisfaction with ambulatory care and compliance in older patients. Med Care. 1982;20:606-14.

Lee VW, Leung PY. Glycemic Control and Medication Compliance in Diabetic Patients in a Pharmacist-Managed Clinic in Hong Kong. Am J Health-Syst Pharm. 2004;60:2593-5.

Kalyango JN, Owino E, Nambuya AP. Non-adherence to diabetes treatment at Mulago Hospital in Uganda: Prevalence and associated factors.Afr Health Sci. 2008;8:67-73.

Sweileh W, Aker O, Hamooz S. Rate of Compliance among Patients with Diabetes Mellitus and Hypertension. An-Najah Univ J Res. 2005;19:1-12.

Hernández-Ronquillo L, Téllez-Zenteno JF, Garduño-Espinosa J, González-Acevez E. Factors associated with therapy noncompliance in type-2 diabetes patients. Salud Publica Mex. 2003;45:191-7.

Khattab MS, Abolfotouh MA, Khan MY, Humaidi MA, AlKaldi YM. Compliance and control of diabetes in a family practice setting, Saudi Arabia. East Mediterr Health J. 1999;5:755-65.

Spikmans FJ, Brug J, Doven MM, Kruizenga HM, Hofsteenge GH, van Bokhorst-van der Schueren MA. Why do diabetic patients not attend appointments with their dietitian? J Human Nutr Diet. 2003;16:151-8.

Kyngas H, Lahdenpera T. Compliance of patients with hypertension and associated factors. J Ad Nurs. 1999;29:832-9.

Khan AR, Al-Abdul Lateef ZN, Al Aithan MA, Bu-Khamseen MA, Al Ibrahim I, Khan SA. Factors contributing to non-compliance among diabetics attending primary health centers in the Al Hasa district of Saudi Arabia. J Fam Community Med. 2012;19:26-32.

Ibrahim NK, Attia SG, Sallam SA, Fetohy EM, El-Sewi F. Physicians’ therapeutic practice and compliance of diabetic patients attending rural primary health care units in Alexandria. J Fam CommunityMed. 2010;17:121-8.

Ghods AJ. Nasrollahzadeh D. Noncompliance with Immunosuppressive Medications after Renal Transplantation. Tissue Antigens. 2002;60:553.

Mark A, Benjamin W. Tassell V, Joanne L. Medication Nonadherence: An Unrecognized Cardiovascular Risk Factor. MedGenMed. 2007;9(3):58.

Senior V, Marteau TM, Weinman J. Self-reported adherence to cholesterol-lowering medication in patients with familial hypercholesterolaemia: The role of illness perceptions. J Cardiovasc Drugs Ther. 2004;18:475-81.

Al-Yahya A, Amal M, Al-Ghareeb H. Comparison of Compliance versus Non-Compliance to Antihypertensive Agents in Primary Health Care – An Area Based Study. Kuwait Medical Journal. 2006,38(1):28-32.

Kasznicki J, Glowacka A, Drzewoski J. Type 2 diabetic patients compliance with drug therapy and glycemic control. Diabetologia Doświadczalna i Kliniczna. 2007;7:199-201.

Conlin P, Gerth W, Fox J. Four-year persistence patterns among patients initiating therapy with the angiotensin II receptor antagonist losartan versus other antihypertensive drug classes. Clin Ther. 2001;23:1999-2010.

Hadi N, Rostami-Gooran N. Determinant factors of medication compliance in hypertensive patients of Shiraz, Iran. Arch Iranian Med. 2004;7(4):292-6.