A case report of all-trans retinoic acid-induced pseudotumor cerebri in an adult patient of acute promyelocytic leukemia
Keywords:
All-trans retinoic acid, Pseudotumor cerebri, Adult, Acute promyelocytic leukemiaAbstract
All-trans retinoic acid (ATRA), a derivative of vitamin A, is the first line drug for acute promyelocytic leukemia (APL). At the same time, ATRA is also associated with various side effects, including some life threatening conditions. We describe a case of ATRA-induced pseudotumor cerebri in an adult patient of APL.
Metrics
References
Fenaux P, Chastang C, Chevret S, Sanz M, Dombret H, Archimbaud E, et al. A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group. Blood. 1999;94(4):1192-200.
Lo-Coco F, Avvisati G, Vignetti M, Breccia M, Gallo E, Rambaldi A, et al. Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group. Blood. 2010;116(17):3171-9.
Holmes D, Vishnu P, Dorer RK, Aboulafia DM. All-Trans retinoic acid-induced pseudotumor cerebri during induction therapy for acute promyelocytic leukemia: a case report and literature review. Case Rep Oncol Med. 2012;2012:313057.
Friedman DI, Jacobson DM. Diagnostic criteria for idiopathic intracranial hypertension. Neurology. 2002;59(10):1492-5.
Vanier KL, Mattiussi AJ, Johnston DL. Interaction of all-trans-retinoic acid with fluconazole in acute promyelocytic leukemia. J Pediatr Hematol Oncol. 2003;25(5):403-4.
Naithani R, Kumar R, Mishra P. Pseudotumor cerebri in a child in early phase of induction therapy for APL with ATRA. Indian J Pediatr. 2009;76(4):439-40.
Anoop TM, Jain N, Nair SG, Narayanan G. All-trans-retinoic acid-induced pseudotumor cerebri in acute promyelocytic leukemia. J Neurosci Rural Pract. 2014;5(3):273-5.
Available at http://www.chemocare.com/chemotherapy/drug-info/atra.aspx#.U-TvoeOSwwA. Accessed 08 August 2014.
Jindal M, Hiam L, Raman A, Rejali D. Idiopathic intracranial hypertension in otolaryngology. Eur Arch Otorhinolaryngol. 2009;266(6):803-6.
Spector RH, Carlisle J. Pseudotumor cerebri caused by a synthetic vitamin A preparation. Neurology. 1984;34(11):
-11.
Visani G, Bontempo G, Manfroi S, Pazzaglia A, D’Alessandro R, Tura S. All-trans-retinoic acid and pseudotumor cerebri in a young adult with acute promyelocytic leukemia: a possible disease association. Haematologica. 1996;81(2):152-4.
Wang SJ, Silberstein SD, Patterson S, Young WB. Idiopathic intracranial hypertension without papilledema: a case-control study in a headache center. Neurology. 1998;51(1):245-9.
Tiamkao S, Sirijirachai C. Pseudotumor cerebri caused by all-trans-retinoic acid: a case report. J Med Assoc Thai. 2000;83(11):1420-3.
Tanaka T, Akifuji Y, Mori M, Ueki J, Nakamoto S. Intracranial hypertension in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid. Rinsho Ketsueki. 1997;38(1):47-51.
