Thalidomide induced xerosis: an unwanted reaction

Authors

  • Nagesh Kamath Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
  • Anurag Shetty Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
  • Harneet Singh Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
  • Shiran Shetty Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
  • Srinivasa Rao Sirasanagandla Department of Anatomy, Melaka Manipal Medical College (Manipal Campus), Manipal University, Manipal, Karnataka, India

Keywords:

Anemia, Gastric antral vascular ectasia, Thalidomide, Xerosis

Abstract

A 59-year-old male exhibited anemia for evaluation. Endoscopy was diagnostic of gastric antral vascular ectasia. He was given a trial of thalidomide after informing about the adverse effects. After starting thalidomide at 100 mg/day, his hemoglobin (Hb) improved. Post 1 month of therapy his Hb normalized, but he developed xerosis. He was given symptomatic treatment, but did not improve. Thalidomide was suspected to cause xerosis, it was discontinued for a month and post-discontinuation of drug he is symptom free for past 8 months. This paper reports a rare case of thalidomide induced xerosis with dermatological and neurological involvement.

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Published

2017-01-25

How to Cite

Kamath, N., Shetty, A., Singh, H., Shetty, S., & Sirasanagandla, S. R. (2017). Thalidomide induced xerosis: an unwanted reaction. International Journal of Basic & Clinical Pharmacology, 3(4), 732–735. Retrieved from https://www.ijbcp.com/index.php/ijbcp/article/view/1064

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Section

Case Reports