TY - JOUR AU - Suddek, Ghada M. PY - 2017/01/02 Y2 - 2024/03/29 TI - Montelukast: much more than an antiasthma drug JF - International Journal of Basic & Clinical Pharmacology JA - Int J Basic Clin Pharmacol VL - 3 IS - 2 SE - Review Articles DO - UR - https://www.ijbcp.com/index.php/ijbcp/article/view/418 SP - 255-259 AB - <p>Montelukast (MK), a selective leukotriene D4 receptor antagonist, is used mainly to reduce eosinophilic inflammation in asthmatic patients. The primary objective of this mini-review is to describe novel additional targets for MK besides the lung and to highlight its antioxidant potential. Literature published between 2002 and 2013 was reviewed for significant antioxidant and anti-inflammatory properties of MK in various experimental models of inflammation rather than that in the airways of asthmatics. Evidence suggests the potential use of MK in many inflammatory diseases rather than asthma therapy.</p> ER -