@article{Khan_Vishwakarma_Giri_Bansal_2017, title={A prospective study on sleep disorders related to antidepressant drugs use in a tertiary care teaching hospital}, volume={4}, url={https://www.ijbcp.com/index.php/ijbcp/article/view/843}, DOI={10.18203/2319-2003.ijbcp20150392}, abstractNote={<p class="ABS" align="left"><span class="Bold">Background:</span> Prescription of antidepressants has been increased from the last decade and responsible for producing sleep disorders as adverse drug reactions (ADRs). Sleep disorders can be divided into 3 large groups: (1) insomnia, (2) primary complaint of daytime sleepiness, and (3) Association of disruptive behaviours during sleep, the disorders of arousal. So active surveillance is needed to access these ADRs.</p><p class="ABS" align="left"><span class="Bold">Aims and Objective:</span> To analyze the sleep disturbances as ADRs of various antidepressants prescribed to the patients attending psychiatry outpatient department (OPD).</p><p class="ABS" align="left"><span class="Bold">Methods:</span> This prospective study was conducted on patients aged ≤74 years attending Department of Psychiatry OPD and were prescribed Antidepressants for the duration of 8 months (December, 2013-July, 2014). The ADRs reported were confirmed by WHO UMC Causality Assessment Scale.</p><p class="ABS" align="left"><span class="Bold">Results:</span> Total number of patients enrolled on the basis of inclusion and exclusion criteria (n=50). Total number of ADRs related to drugs prescribed were found to be n=69. Total number of patients with sleep disturbances as ADRs were found to be n=28.</p><p class="ABS" align="left"><span class="Bold">Conclusion:</span> The drug, most frequently implicated to cause sleep disturbances, was mirtazapine. Increased sleep was the most common ADR, found to occur. Unusual ADRs such as sleep talking was also seen.</p>}, number={4}, journal={International Journal of Basic & Clinical Pharmacology}, author={Khan, Farhan Ahmad and Vishwakarma, Kirti and Giri, Vishal P. and Bansal, Chitrak}, year={2017}, month={Jan.}, pages={787–791} }