@article{Goel_Pathak_Nim_Singh_Dixit_Chaurasia_2017, title={Evaluation of analgesic activity of Emblica officinalis in albino rats}, volume={3}, url={https://www.ijbcp.com/index.php/ijbcp/article/view/436}, abstractNote={<p><strong>Background: </strong>Amla is one of the most often used herbs in indigenous medicine,<strong> </strong>whose all parts including fruit, seed, leaves, root, bark, and flowers are used in various Ayurvedic/Unani medicines. However, studies to establish analgesic potential of amla were limited, so the purpose of the present study was to evaluate analgesic activity of amla, if it possesses any.</p><p><strong>Methods: </strong>Albino rats were divided randomly in three groups of six rats each. Group 1<strong> </strong>(control) received distilled water orally, Group 2 (test) received <em>Emblica officinalis</em> extract in dose of 600 mg/kg orally and Group 3 (standard) received Pentazocine in dose 10 mg/kg intraperitoneally.</p><p><strong>Results: </strong><em>Emblica officinalis</em><strong> </strong>extract did not produced statistically significant (p>0.05)<strong> </strong>analgesia when compared with the control group in hot plate latency, but produced a statistically significant reduction in 6% NaCl induced abdominal writhing (p<0.05). <strong>Conclusions: </strong>Since the plant extract significantly reduced the number of writhes in<strong> </strong>abdominal writhing model, but do not increase hot plate latency, the commercially available crude extract of <em>Emblica officinalis</em> exhibit analgesic activity involving peripheral mechanisms.</p>}, number={2}, journal={International Journal of Basic & Clinical Pharmacology}, author={Goel, Bhomik and Pathak, Nishant and Nim, Dwividendra Kumar and Singh, Sanjay Kumar and Dixit, Rakesh Kumar and Chaurasia, Rakesh}, year={2017}, month={Jan.}, pages={365–368} }