Garenoxacin as a prophylactic anti-infective in hydropneumothorax: a case study report

Shahid Haider, Anoop L. Hajare, K. Krishnaprasad, Amit Bhargava


Pneumothorax appears to be a common clinical state. Iatrogenic pneumothorax occurs commonly after procedures such as transthoracic needle biopsy, pleural biopsy, positive pressure ventilation, etc. Diagnosis of iatrogenic pneumothorax is often delayed. Broad spectrum anti-infectives appear to be beneficial in reducing the infections, especially when chest drains are inserted. Garenoxacin, a potent quinolone with its unique structural modification appears to have an edge over other respiratory quinolones.


Pneumothorax, Iatrogenic, Garenoxacin, Chest drain

Full Text:



MacDuff A, Arnold A, Harvey J, BTS Pleural Disease Guideline Group. Management of spontaneous pneumothorax: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010;65 Suppl 2:ii18-31.

Henry M, Arnold T, Harvey J, Pleural Diseases Group, Standards of Care Committee, British Thoracic Society. BTS guidelines for the management of spontaneous pneumothorax. Thorax. 2003;58 Suppl 2:ii39-52.

Ghezel-Ahmadi D, Bölükbas S, Fischer T, Ghezel-Ahmadi V, Schirren J. Pneumothorax, what kind of therapy is necessary? A clinical overview. Zentralbl Chir. 2012;137(3):214-22.

Noppen M, De Keukeleire T. Pneumothorax. Respiration. 2008;76(2):121-7.

Loiselle A, Parish JM, Wilkens JA, Jaroszewski DE. Managing iatrogenic pneumothorax and chest tubes. J Hosp Med. 2013;8(7):402-8.

Withers JN, Fishback ME, Kiehl PV, Hannon JL. Spontaneous pneumothorax. Suggested etiology and comparison of treatment methods. Am J Surg. 1964;108:772-6.

Bense L, Eklund G, Wiman LG. Smoking and the increased risk of contracting spontaneous pneumothorax. Chest. 1987;92(6):1009-12.

Grover FL, Richardson JD, Fewel JG, Arom KV, Webb GE, Trinkle JK. Prophylactic antibiotics in the treatment of penetrating chest wounds. A prospective double-blind study. J Thorac Cardiovasc Surg. 1977;74(4):528-36.