Prescribing pattern of antimicrobial agents in pediatrics department of a teaching hospital
Keywords:Antibiotics, Pediatrics, Rational use of drugs
Background: Antibiotics are commonly used in pediatric illness and irrational use of antibiotics can lead to bacterial resistance. Appropriate studies should be done to frame proper guidelines for the use of antibiotics in pediatric population. The objective of the study was to determine the prescribing pattern of antibiotics and to analyze the rational use of antibiotics in pediatric department.
Methods: An observational prospective study was carried out for a period of 3 months in the Department of Pediatrics. The data were recorded in the specific format, and the result was analyzed by descriptive statistics.
Results: In this study, 347 prescriptions containing antibiotics were analyzed, out of which 54.6% were of male child and 45.4% were of female child. About 40.6% of the patients were in the age group of 1-5 years. A single antibiotic was prescribed in 78% of patients. Respiratory tract infections were the most common disease (68.2%), followed by skin infections (12.3%), gastrointestinal diseases (9.5%), and fever without focus (6.5%). Cephalosporins were the most commonly prescribed antibiotic group (35%).
Conclusion: Irrational use of antibiotics can lead to bacterial resistance and can worsen the existing disease conditions. So, antibiotics should be prescribed according to the WHO guidelines or other rational strategy, especially in the pediatric age group.
Sanz EJ, Bergman U, Dahlstorm M. Paediatric drug prescribing. Eur J Clin Pharmacol. 1989;37(1):65-8.
Summers RS, Summers B. Drug prescribing in paediatrics. Ann Trop Paediatr. 1986;6(2):129-33.
Principi N, Marchisio P, Sher D, Boccazzi A, Moresco RC, Viola G, et al. Control of antibiotic therapy in paediatric patients. Dev Pharmacol Ther. 1981;2(3):145-55.
Schollenberg E, Albritton WL. Antibiotic misuse in a pediatric teaching hospital. Can Med Assoc J. 1980;122(1):49-52.
Dr. Ipp M. Reduced antibiotic use in a Paediatric practice: Practical office strategies based on current evidence. Published in June 2000.Available at http://sites.utoronto.ca/kids/aboveruse.htm.
Choudhury DK, Bezbaruah BK. Antibiotic prescriptions pattern in paediatric in-patient department Gauhati medical college and hospital, Guwahati. J App Pharm Sci. 2013;3(8):144-8.
Palikhe N. Prescribing pattern of antibiotics in pediatric hospital of Kathmandu valley. J Nepal Health Res Counc. 2004;2(2):31-6.
Orrett FA, Changoor E, Maharaj N. Pediatric drug prescribing in a regional Hospital in Trinidad. J Chin Clin Med. 2010;5(3):157.
van Houten MA, Luinge K, Laseur M, Kimpen JL. Antibiotic utilisation for hospitalised paediatric patients. Int J Antimicrob Agents. 1998;10(2):161-4.
Sriram S, Leo M, Manjula Devi AS, Rajalingam B, Ramkumar K, Rajeswari R. Assessment of antibiotic use in pediatric patients at a tertiary care teaching hospital. Indian J Pharm Pract. 2008;1(1):30-6.
van der Meer JW, Gyssens IC. Quality of antimicrobial drug prescription in hospital. Clin Microbiol Infect. 2001;7 Suppl 6:12-5.
Feleke M, Yenet W, Lenjisa JL. Prescribing pattern of antibiotics in pediatric wards of Bishoftu Hospital, East Ethiopia. Int J Basic Clin Pharmacol. 2013;2(6):718-22.
Finkelstein JA, Stille C, Nordin J, Davis R, Raebel MA, Roblin D, et al. Reduction in antibiotic use among US children, 1996-2000. Pediatrics. 2003;112(3):620-7.