Emergence of resistant pathogens against colistin


  • Rakesh Kumar Department of Pharmacology, Punjab Institute of Medical Sciences, Jalandhar, Punjab, India
  • Baljit Jassal Department of Pharmacology, Punjab Institute of Medical Sciences, Jalandhar, Punjab, India,
  • Bhupinder Kumar Department of Cardiology, Dayanand Medical College, Ludhiana, Punjab, India




Resistant, Gram-negative bacilli, Colistin, Pseudomonas aeruginosa


Emergence of resistant strain to antimicrobials is a growing problem worldwide. Here, we report a case of multidrug-resistant Klebsiella pneumoniae and Acinectobacter baumannii, Gram-negative bacilli, which was only intermediate sensitive to colistin; a polymyxin E. Colistin has attracted more interest recently because of its significant activity against multi-resistant Pseudomonas aeruginosa, A. baumannii and K. pneumoniae, and the low resistance rates to it. The decrease in sensitivity of colistin against K. pneumoniae and A. baumanni sends alarming signals for the development of resistance to this antimicrobial drug. It is likely that colistin the important antimicrobial option against multi-resistant Gram-negative bacteria will be lost.


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How to Cite

Kumar, R., Jassal, B., & Kumar, B. (2017). Emergence of resistant pathogens against colistin. International Journal of Basic & Clinical Pharmacology, 4(3), 593–595. https://doi.org/10.18203/2319-2003.ijbcp20150027



Case Reports