Drug utilization study of psychotropic drugs in outdoor patients in a tertiary care hospital attached with a medical college

Chintan Madhusudan Doshi, Rutvij Hedamba, Nishita H. Darji, Bansari Patel, Hiren R. Trivedi, Deepak Tiwari


Background: Psychotropic drugs have a great importance in psychiatric practice. Today many newer drug like selective serotonin reuptake inhibitors and atypical antipsychotic drugs has changed treatment protocol. Hence, the study was carried out to find morbidity pattern of psychiatric illness and prescribing pattern of psychiatric illness.

Methods: A prospective cross-sectional study was carried out for 12 months. Patients of all ages and both sexes were included in the study while inpatients and referred patients were excluded. The prescribing pattern was analyzed by using World Health Organization (WHO) basic drug indicators.

Results: Among 600 patients, male patient were 291 (48.50%) and female patient were 309 (51.50%). The most common disorder was depression 208 (34.66%) followed by schizophrenia 192 (32.00%). The numbers of psychotropic drugs prescribed a patient were 2.51. 39.39% drugs were prescribed from the WHO essential medicines list. Total 89.18% drugs were prescribed by generic name. Benzodiazepines were the most common prescribed drugs. Atypical antipsychotic drugs were commonly used than typical antipsychotic drugs. Central anticholinergic drug was used in 43.15% patients receiving antipsychotic drugs.

Conclusion: Overall, the drugs were prescribed rationally. Benzodiazepine should be prescribed only for short-term duration. Use of central acting anticholinergic drugs with all antipsychotic drugs was not justified.


Drug utilization, Prescribed daily dose, Psychotropic drugs, Prescribing pattern

Full Text:



Lee D, Bergmen U. Studies of utilization. In: Strom BC, editor. Pharmacoepidemiology. 1st Edition. New York: Churchill Livingstone; 1989: 259-73.

Introduction to Drug Utilization Research by World Health Organization. Available at archive/publications/drug_utilization_research.pdf. Accessed 10 September 2014.

Thakkar KB. A drug utilization study of psychotropic drugs prescribed in the psychiatry outpatient department of a tertiary care hospital. J Clin Diagn Res. 2013;7(12):2759-64.

Murthy R. Mental health programme in the 11th five year plan. Indian J Med Res. 2007. Available at;year=2007;volume=125;issue=6;spage=707;epage=711;aulast=Murthy;type=0. Cited 14 August 2015.

Piparva KG. Drug utilization study of psychotropic drugs in outdoor patients in a teaching hospital. Indian J Psychol Med. 2011;33(1):54-8.

Rode SB. A study on drug prescribing pattern in psychiatry out-patient department from a tertiary care teaching hospital. Int J Basic Clin Pharm. 2014;3(3):517-40.

Sadock BJ, Sadoc VA. Kaplan and Sadock’s Synopsis of Psychiatry. 10th Edition. New York: Lippincott Williams and Wilkins; 2007: 1020-50.

Stein DJ, Der NV, Tasman MA, Erik Simonsen KN, Ronningstam E. Textbook of Psychiatry. 1st Edition. New Delhi: Churchill Livingstone; 2002: 27.

Memon A. Drug use pattern of antidepressant agents in psychiatric patients – A prospective study. NHL J Med Sci. 2013;2(2):32-6.

Lahon K. Pharmacoepidemiological study of antipsychotics in the psychiatry unit of a tertiary care hospital: a retrospective descriptive analysis. Int J Nutr Pharm Neurol Dis. 2012;2(2):135-42.

Dewa CS, Remington G, Herrmann N, Fearnley J, Goering P. How much are atypical antipsychotics being used, and do they reach the populations who need them? A Canadian experience. Clin Ther. 2002;24:1466-76.

Chou LF. Patterns and costs of antipsychotic drug use in Taiwan: 1997-2001. Adv Ther. 2003;20:344-51.

Monshat K, Carty B, Olver J, Castle D, Bosanac P. Trends in antipsychotic prescribing practices in an urban community mental health clinic. Australas Psychiatry. 2010;18:238-41.

Dhasmana DC, Rawat Y, Mishra KC. What is so atypical about atypical antipsychotic? Indian J Pharmacol. 2003;35:322-4.

Brasic JR. Tardive Dyskinesia. Medscape Reference: drugs, Diseases and Procedures; 2012. Available at Cited 12 September 2014.

Kane J. Tardive dyskinesia: epidemiological and clinical presentation. In: Davis KL, Charney D, Coyle JT, Nemeroff C, editors. Neuropsychopharmacology. 5th Edition. Generation of Progress. Philadelphia, Pennsylvania: Lippincott, Williams, and Wilkins; 2002. Available at Accessed 18 July 2015.

NICE. Anxiety (CG22). National Institute for Health and Clinical Excellence. National Collaborating Centre for Mental Health; 2011. Available at Cited 14 August 2015.