Prescribing pattern of antibiotics in pedodontics OPD of tertiary care dental hospital in Dhule district

Swapnil Balkrishna Kaikade, Nitin Dnyaneshwar Pise


Background: Antibiotics are prescribed in dental practice for prophylactic and therapeutic reasons. Prophylactic antibiotics are prescribed to prevent diseases caused by members of the oral flora introduced to distant sites in a host at risk or introduced to a local compromised site in a host at risk. Although a number of studies on antibiotic use have been carried out, controversies still exist in areas such as prophylaxis, interactions and their use after both minor and intermediate oral surgical procedures. These controversies lead to inappropriate and unnecessary antibiotic use in humans. The objective of this study was to study prescribing frequency of antimicrobial agents and to study prescribing frequency of particular brand of antibiotic agent.

Methods: A descriptive study was conducted in outpatient department of pedodontics of a tertiary care teaching hospital. Three hundred prescriptions were randomly collected over a period of 30 days. The data was then analysed to find out the prescribing pattern.

Results: In the present study, 67% of the total prescriptions had at least one antibiotic and amoxicillin is the most frequently prescribed antibiotic while co-amoxyclav is the most frequently prescribed fixed dose combination. Amongst fixed dose combination of amoxycillin and clavulanic acid, megamox CV (55%) is the most frequently prescribed brand followed by moxclav kid (34%). For amoxycillin, novamox (60%) is the most frequently prescribed brand followed by moxkid (31%) and megamox (8%).

Conclusions: Most reports on antibiotic use in dentistry show amoxicillin or other penicillin-based drugs to be the most commonly used. This trend is based on the established efficacy of penicillin based drugs on bacteria involved in odontogenic infections. Increasingly resistant strains are being reported in odontogenic infections, hence the need for constant antibiotic pharmacovigilance.


Prescription pattern, Antibiotics, Pedodontics, OPD

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Tripathi KD. Antimicrobial drugs: general considerations; essentials of medical pharmacology; 7th Ed.

Montazem A. Antibiotic prophylaxis in dentistry. Mt Sinai J Med. 1998;65;388-92.

Poeschl PW, Eckel D, Poeschl E. Postoperative prophylactic antibiotic treatment in third molar surgery- a necessity? J Oral Maxillofac Surg. 2004;62:3-8.

Dajani AS, Taubert KA, Wilson W, Bolger AF, Bayer A, Ferrieri P, et al. Prevention of bacterial endocarditis: recommendations of american heart association. J Am Dent Assoc. 1997;277:1794-801.

Fine DH, Hammond BF, Loesche WJ. Clinical use of antibiotics in dental practice. Int J Antimicrob Agents. 1998;9:235-8.

Van De, Grundmann H, Verloo D, Tiemersma E, Monen J, Goossens H, et al. Antimicrobial drug use and resistance in Europe. Emerg Infect Dis. 2008;14:1722-30.

Peterson LJ. Antibiotics: their use in therapy and prophylaxis. In: Topazian RG, Goldenberg MH, eds. Management of infections of the oral and maxillofacial region. 2nd ed. Philadelphia: WB Saunders Company; 1987.

American dental council on antibiotic use in dentistry. J Am Dent Assoc. 1997;128:64-8.

Tenover FC, Hughes JM. The challenges of emerging infectious diseases: development and spread of multiply-resistant bacterial pathogens. J Am Med Assoc. 1996;275:300-4.

Smith A, Bagg J. An update on antimicrobial chemotherapy, 3: antimicrobial resistance and the oral cavity. Dent Update. 1998;25:230-4.

American dental association council on scientific affairs. Antibiotic use in dentistry. J Am Dent Assoc. 1997;128:648.

Ashrafian H, Bogle RG. Antimicrobial prophylaxis for endocarditis: emotion or science? Heart. 2007;93:5-6.

Council on clinical affairs. Guidelines on appropriate use of antibiotic therapy for pediatric dental patients. In: American academy of pediatric entistry reference manual. American Academy of Pediatric Dentistry. 2010;29:246-8. Available at

Yehuda Z, Liran L. Clinical decision making in restorative dentistry, endodontics, and antibiotic prescription. J Dent Educ. 2008;72:81-6.

Salako NO, Rotimi VO, Adib SM, Al-Mttawa S. Pattern of antibiotic prescription in the management of oral diseases among dentists in Kuwait. J Dent. 2004;32:503-9.

Demirbas F, Gjermo P, Preus HR. Antibiotic prescribing practices among Norwegian dentists. Acta Odontal Scand. 2006;64;355-9.