Efficacy and tolerability of vitamin C as an add on therapy to standard antihypertensive regimen

Authors

  • Vivek Singh Department of Pharmacology, Saraswathi Institute of medical sciences, Hapur, Uttar Pradesh, India
  • Ujjwal Sourav Department of Community medicine, Saraswathi Institute of medical sciences, Hapur, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20205545

Keywords:

Adenomysis, Abnormal uterin bleeding, MR hysterography

Abstract

Background: In both developing and developed countries, elevated arterial blood pressure is perhaps the most significant public health issue. It is widespread, often asymptomatic, readily observable, typically easily treatable and, if left untreated, frequently leads to lethal complications. According to the Framingham report, the prevalence of hypertension in the white suburban population is almost one-fifth of those with blood pressure >160/95 mm Hg, while almost half of those with blood pressure >140/90 mm Hg. Aim and objectives were to estimate the efficacy of vitamin C as an add-on therapy to the antihypertensive regimen.

Methods: The prospective comparative study was undertaken in mild to moderate hypertensive patients to find out the efficacy and tolerability of vitamin C as an add-on therapy to the standard anti-hypertensive regimen in the reduction of blood pressure and C-reactive protein levels. This study was done at the Saraswathi institute of medical sciences, Hapur, UP.

Results: For Systolic BP as well as DBP, at baseline there was non-significant difference among all the four group with p value 0.28, whereas at all the visit at 1, 3 and 6 month there was significant difference among the four group with p value<0.01, <0.001 and<0.001.

Conclusions: There was significant addon benefit of vit C when added with standard antihypertensive regimen.

Author Biographies

Vivek Singh, Department of Pharmacology, Saraswathi Institute of medical sciences, Hapur, Uttar Pradesh, India

Associate Professor, Department of Pharmacology

Ujjwal Sourav, Department of Community medicine, Saraswathi Institute of medical sciences, Hapur, Uttar Pradesh, India

ASSISTANT PROFESSOR, COMMUNITY MEDICINE

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Published

2020-12-23

How to Cite

Singh, V., & Sourav, U. (2020). Efficacy and tolerability of vitamin C as an add on therapy to standard antihypertensive regimen. International Journal of Basic & Clinical Pharmacology, 10(1), 90–94. https://doi.org/10.18203/2319-2003.ijbcp20205545

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Section

Original Research Articles