Pattern of anti-diabetic drugs prescribed for type 2 diabetes mellitus patients in a tertiary care hospital of India: an observational study


  • Ajita Kapur Department of Pharmacology, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India
  • Harmeet Singh Rehan Department of Pharmacology, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India
  • Lalit Kumar Gupta Department of Pharmacology, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India
  • Madhur Yadav Department of Medicine, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India



Diabetes mellitus type 2, Drug utilization, Prescription study


Background: Type 2 diabetes mellitus (T2DM) is a leading cause of significant morbidity and mortality in developing countries. Evaluation of anti-diabetic drug use pattern guides the healthcare professionals to identify early signals of irrational prescribing and to plan interventions to optimize the benefits of pharmacotherapy.

Methods: Observational descriptive study was conducted on 500 prescriptions of T2DM patients collected from Outpatient department of a tertiary care hospital. Prescriptions were analysed for type, number, generic/brand names, fixed dose combinations (FDCs) of anti-diabetic drugs and anti-diabetic drugs prescribed from within National List of Essential Medicines (NLEM) 2015.

Results: Average number of anti-diabetic drugs per prescription was 2.5. Of these 49% were from within NLEM and only 39% were prescribed by their generic names. Among all the anti-diabetic groups of drugs used, biguanide (32.85%) was the most frequently prescribed followed by insulins (25.4%) and DPP-4 inhibitors (13.75%). Combined drug therapy was more prevalent than monotherapy (70% versus 30%). Metformin+sitagliptin and metformin+linagliptin were most commonly prescribed fixed dose combinations.

Conclusions: Recent trend of anti-diabetic drug use included newer anti-diabetic drugs in combination with metformin to achieve better euglycemia and to minimize complications of T2DM.


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How to Cite

Kapur, A., Rehan, H. S., Gupta, L. K., & Yadav, M. (2019). Pattern of anti-diabetic drugs prescribed for type 2 diabetes mellitus patients in a tertiary care hospital of India: an observational study. International Journal of Basic & Clinical Pharmacology, 8(7), 1657–1661.



Original Research Articles