A study to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy

Amit Kumar; Kusum Kumari; Priyanki .; Pranay Kumar Mishra

doi:10.18203/2319-2003.ijbcp20183493

Authors

Amit Kumar Department of Medical Oncology, Brahmanand Narayan Hrudyalay, Jamshedpur, Jharkhand Province, India
Kusum Kumari Department of Pharmacology and Therapeutics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand Province, India
Priyanki . Department of Pharmacology and Therapeutics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand Province, India
Pranay Kumar Mishra Department of Surgery, Tinplate Hospital, Jamshedpur, Jharkhand, Province, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20183493

Keywords:

Chemotherapy, GM-CSF, Total leucocyte count, Total platelet count

Abstract

Background: The aim of the present study was to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy.

Methods: The total leucocyte count (TLC) and total platelet count (TPC) of thirty patients on chemotherapy were obtained before and after the administration of GM-CSF. The results were analysed retrospectively for the effect of GM-CSF on these parameters. Statistical analysis was done, and graphs were made by Libre office calc and Student’s T Test was used for comparison of data.

Results: The study showed that EMGRAST-M had an impressive effect on both the platelet count and the leucocyte count.

Conclusions: GM-CSF has a great therapeutic role in the enhancement of platelet count and leucocyte count in patients of cancer chemotherapy.

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