Impact of educational session on knowledge and attitude towards teratogenicity among undergraduate medical students: a comparative study

Priyanka Kumari, Vasundara Krishnaiah, Girish Kumaraswamy, Tushar J. Tamboli


Background: Teratogenicity is a major cause of abortion, still birth and can result in longterm disability with a significant impact on individuals, families, societies and healthcare systems. Drugs being one of the causes of teratogenicity, creating awareness among medical students, the future prescribing physicians, the rate of teratogenicity can be decreased. The objective was to compare the attitude and knowledge about teratogenicity among the medical undergraduates before and after an educational session on teratogenicity.

Methods: A pre-validated semi structured questionnaire on attitude and knowledge about teratogenicity was distributed to 2nd year medical students (147) before and after teratogenicity educational session. Results obtained were compared within the group. Paired t test was used for within the group comparison. P-Value <0.05 was considered to be statistically significant.

Results: Improvement in knowledge showed statistically significant improvement following teratogenicity educational session (P-Value=0.0003). Improvement was there in post session attitude scores as well, however, it was not significant (P-Value=0.64).

Conclusions: Early reinforcement about teratogenicity in medical students enables them to decide appropriate drug therapy while prescribing for females of reproductive age group.


Knowledge, Teratogenicity, Undergraduate medical students

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Bisht M, Dhasmana DC. Teratagenecity and Maternogenicity. Myths and Facts. RJPBCS. 2014;5(1):452-69.

Sharma R. Birth defects in India: Hidden truth, need for urgent attention. Indian J Hum Genet. 2013;19(2):125-9.

Alwan S, Chambers CD. Identifying Human Teratogens: An Update. J Pediatr Genet. 2015;4:39-41.

World Health Organization. Fact sheet: Congenital anomalies, 2016. Available at: Accessed 14 August 2017.

National Health Portal. Congenital anomalies (birth defects), 2016. Available at: Accessed 14 August 2017.

Kar A. Birth Defects in India: Magnitude, Public Health Impact and Prevention. JKIMSU. 2014;3(2):7-16.

Chauhan PR, Mehta RV, Chauhan GR, Chauhan B, Rathi S. A study of Prescription of Potentially Teratogenic Medications to the females of Reproductive age group (14-45 years) in Surendranagar. Int J Biol Med Res. 2012;3(2):1498-501.

Feldkamp ML, Carey JC, Byrne JL, Krikov S, Botto LD. Etiology and clinical presentation of birth defects: Population based study. BMJ. 2017;357:j2249.

Sachdeva P, Patel BG, Patel BK. Drug Use in Pregnancy; a Point to Ponder. Ind J Pharm Sci. 2009 JanFeb;71(1):1-7.

Khan AK, Banu G. A questionnaire based survey on knowledge, attitude and practices of medical practitioners regarding the prescribing of medications during pregnancy. Int J Reprod Contracept Obstet Gynecol. 2016 Apr;5(4):984-8.

Kureshee NI, Dhande PP. Awareness of Mothers and Doctors about Drug Utilization Pattern for Illnesses Encountered during Pregnancy. J Clin Diagn Res. 2013;7(11):2470-4.

Centers for Disease Control and Prevention. Understanding the Causes of Major Birth Defects: Steps to Prevention, 2015. Available at: Accessed 14 August 2017.

Tamboli TJ, Pundarikaksha HP, Ramaiah M, Bhatt KA, Prasad SR. Impact of educational session on knowledge and attitude towards antimicrobial prescribing and awareness about antimicrobial resistance among undergraduate medical, dental and nursing students: a comparative study. Int J Basic Clin Pharmacol. 2016;5:1544-50.

Divyalasya TVS, Vasundara K, Pundarikaksha HP. Impact of educational session on knowledge and attitude toward palliative care among undergraduate medical, nursing and physiotherapy students: a comparative study. Int J Basic Clin Pharmacol. 2014;3:442-6.

Nisar YB, Alam A, Aurangzeb B, Dibley MJ. Perceptions of antenatal iron-folic acid supplements in urban and rural Pakistan:a qualitative study. BMC Pregnancy and Childbirth. 2014;14:344.

Wilcock J, Strivens J. A study to enhance medical students’ professional decision-making, using teaching interventions on common medications. Medical education online. 2015;20:1.