DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20172238

Study of prevalence and prescribing trends in infectious diseases: as a teaching tool for MBBS 2nd professional students

Mirza A. Beg, Shakti B. Dutta, Shalu Bawa, Amanjot Kaur, Subhash Vishal

Abstract


Background: Irrational prescription of drugs is a common occurrence in clinical practice. Introduction of clinical pharmacology at the undergraduate level as an integral part of rational therapeutics is the need of hour. The present drug utilization study, prevalence and prescribing pattern in infectious diseases in a tertiary care teaching hospital was carried out to teach clinical pharmacology to 2nd professional MBBS students, to sensitize and promote rational prescribing.

Methods: A total of 621 prescriptions were collected by 2nd professional MBBS students at Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun. Prescriptions were analyzed on various parameters, using WHO drug use indicators.

Results: A total of 621 prescriptions were analyzed. 477 (76.81%) were males and 144 (23.19%) were females. Majority of patients 357 (57.49%) were 16-60 years’ age group. The infectious diseases prevalence was 153 (24.63%) enteric fever, 132 (21.26%) hepatitis, 111 (17.87%) pyrexia of unknown origin, 90 (14.49%) cellulitis, 135 (21.74%) belongs to miscellaneous category respectively. A total of 4446 drugs were prescribed, which includes antibiotics 2025 (45.55%), multivitamins 969 (21.79%), antacids 699 (15.72%), analgesics 408 (9.18%), antiemetic 273 (6.14%) and antiepileptic 72 (1.62%) respectively. 3096 (69.64%) oral, 1350 (30.36%) injectable and 786 (17.68%) fixed dose combinations (FDCs) were prescribed. 3.26 antibiotics and 7.15 drugs per prescription were prescribed. 2622 (58.97%) drugs were prescribed from national essential medicine list 2015. 100% drugs were prescribed by brand names.

Conclusions: The prescriptions revealed polypharmacy. This study can help to provide feedback to the prescribers, thereby increase in awareness and improve patient care by rational utilization of drugs.


Keywords


Clinical pharmacology, Infectious diseases, Prescribing pattern

Full Text:

PDF

References


Nandi PL, Chan JNF, Chan CPK, Chan P, Chan LPK. Undergraduate medical education: comparison of problem-based learning and conventional teaching. HKMJ. 2000;6:301-6.

Gitanjali B, Shashindran CH. Curriculum in clinical pharmacology for medical undergraduates of India. Indian J Pharmacol. 2006;38:108-14.

Kaushal S, Chopra SC, Arora S. Modifications in the undergraduate MBBS pharmacology practical curriculum: The DMCH model. Indian J Pharmacol. 2007;39(1):57-9.

Revrathi R, Gopalkrishnan S. Study of notifiable infectious diseases reported to a tertiary care teaching hospital in Kancheepuram, District of Tamil Nadu. Nat. J. Res. Com. Med. 2014;41-6.

John TJ, Dandona L, Sharma VP, Kankar M. Continuing challenge of infectious diseases in India. Lancet. 2011;13:252-69.

Ghosh R, Neogi JN, Srivastva BS, Sen P. Prescribing trends in a teaching hospital in Nepal. JNMA. 2003;42:340-49.

Bhattacharya A, Gupta H, Dewangan MK. Prescribing pattern study of drugs used in a tertiary hospitals of the Bilaspur region. Asian J of Pharmaceutical and Clinical Research. 2012;5:73-6.

Biswas M, Roy DN, Rahman M, Islam M, Parvez M, Haque U, Shahriar AAE et al. Prescribing trends of antibiotics for outpatients in Bangladesh: A cross sectional health survey conducted in three districts. IJPSR. 2014;19:669-75.

Ansari KU, Singh S, Pandey RC. Evaluation of prescribing pattern of doctors for rational drug therapy. Indian J Pharmacol. 1998;30:43-6.

Benet LZ. Principles of prescription order writing and patient compliance instructions. In: Hardman JG, Limbard LE, Molinoff PB, Ruddon RW, Gilman AG (editors). Goodman and Gilman’s the pharmacological basis of Therapeutics, 9th Ed. New York: McGraw Hill; 1996:1697-1706.

Sarkar C, Das B. Prescribing trends in a teaching hospital in western Nepal. JNGMC. 2002;2:4-7.

Meher BR, Mukharjee D, Dayshankar U. A study on antibiotic utilization in a general medicine ward of a tertiary care teaching hospital. 2014;6(7):1847-49.

Gupta R, Marko JL. Drug prescription pattern of outpatients in a tertiary care teaching hospital in central India. International J of Bioassays. 2014;3(12):3566-68.

Ola A, Azza A, Mahalli El, Salem AM, Elkahky AA. WHO/INRUD drug use indicators at primary healthcare centres in Alexandria, Egypt. J of Taibah university medical sciences. 2014;9(1):54-64.