Assessment of prescription pattern of cataract patients in the ophthalmology department at a tertiary health care institution

Karishma Adhikari, Bezbaruah B. K.


Background: Evaluation of the current prescription pattern of cataract patients in the Ophthalmology Department to find out utilization of drugs per prescription that reflects possibilities of drug interaction and patient compliance and to suggest measures for rational prescriptions.

Methods: The study was carried out in the Ophthalmology Department at Gauhati Medical College and Hospital, Guwahati for a period of 6 months after obtaining permission from the Institutional Human Ethics Committee. This was a retrospective, observational hospital based study. The present study included patients of any age group and both the sexes (male/female) who were diagnosed as having cataract and who were prescribed different categories of drugs. A total of 156 prescriptions were collected, analysed and classified during the study period (both outdoor and indoor patients).

Results: Our study found that maximum numbers of patients were encountered in the age group of 45-65 years and around 48.4% of cases for IOL implantation were having immature senile cataract. Topical eye drops are most commonly used account for 56.3% in preoperative cases. Overall 564 drugs were prescribed on discharge in 156 prescriptions; So on an average 3.6 drugs were prescribed per prescription. Overall antimicrobials (51.80%) are most commonly prescribed group followed by anti-inflammatory (25.10%), anxiolytic, steroid etc.

Conclusions: Our study showed a significant awareness to avoid polypharmacy by keeping average number of drugs per prescription as low as possible to avoid increased cost of the therapy, therapeutic failure, and adverse drug reactions and hence for better patient compliance.


Antimicrobials, Cataract, IOL Implantation, Polypharmcy, Prescription pattern

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Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo. Harrison’s principles of internal medicine. New York: Mcgraw-Hill; 2012:4022-55.

Bhavikkumar HS, Bhavin V, Divyesh JV, Jasmina SS. Drug Utilization Study in Cataract Patients from South Gujarat Region. Indian Journal of Pharmacy Practice. 2011;4(3):46.

Chang, David F. Antibiotic prophylaxis of postoperative endophthalmitis after cataract surgery: results of the 2014 ASCRS member survey. Journal of Cataract and Refractive Surgery. 2015;41(6):1300-5.

Shah GK, Stein JD, Sharma S. Visual outcomes following the use of intravitreal steroids in the treatment of postoperative endophthalmitis. Ophthalmology. 2000;107(3):486-89.

Nikeghbali A, Falavarjani KG, Kheirkhah A. Pupil dilation with intracameral lidocaine during phacoemulsification. Journal of Cataract and Refractive Surgery. 2007;33(1):101-3.

Shiva F, Eidikhani AL, Padyab M. Prescription practices in acute pediatric infections. Journal of Pediatric Infectious Diseases. 2006;1(1):25-8.

Peuskens J. The evolving definition of treatment resistance. Journal of Clinical Psychiatry; 1999.

Aronson JK. Medication errors: what they are, how they happen, and how to avoid them. QJM. 2009;102(8):513-21.

McDowell SE, Ferner HS, Ferner RE. The pathophysiology of medication errors: how and where they arise. British Journal of Clinical Pharmacology. 2009;67(6):605-13.

Tully MP, Ashcroft DM, Dornan T. The causes of and factors associated with prescribing errors in hospital inpatients. Drug Safety. 2009;32(10):819-36.

Mahar, Michael L. Prescription order packaging system and method. U.S. Patent 6,769,228, issued August 3; 2004.

Hogerzeil HV. Promoting rational prescribing: an international perspective. British journal of clinical pharmacology.1995;39(1):1-6.

Javitt JC, Steinert RF. Cataract extraction with multifocal intraocular lens implantation: a multinational clinical trial evaluating clinical, functional, and quality-of-life outcomes. Ophthalmology. 2000;107(11):2040-8.

Binjawadgi A, Kakkeri RH, Patil BV, Dass P, Raikar S. Drug prescribing pattern in cataract surgery by intra -ocular lens implantation. Journal of Evolution of Medical and Dental Sciences. 2013;35(2):6723-32.

Liesegang TJ. Use of antimicrobials to prevent postoperative infection in patients with cataracts. Current opinion in Ophthalmology. 2001;12(1):68-74.

National eye institute (USA). Facts about Cataract. Maryland: National institute Of Health; 2010[cited 2010 Aug 30]. Available from: URL:

Moroi SE, Lichter PR. Ocular pharmacology. In: Alfred Goodman and Gilman. The Pharmacological Basis of Therapeutics. 9th edition, section XVI, New York: Mcgraw-Hill; 1996.

Reddy MS, Suneetha N, Thomas RK, Battu RR. Topical diclofenac sodium for treatment of postoperative inflammation in cataract surgery. Indian j Opthalmol. 2000;48(3):223-6.