Digoxin toxicity: crucial to diagnose

Authors

  • Tejas A. Acharya Department of Pharmacology, C.U. Shah Medical College and Hospital, Surendranagar 363001, India
  • Dimple S. Mehta Department of Pharmacology, C.U. Shah Medical College and Hospital, Surendranagar 363001, India
  • Ritesh S. Vekariya Department of Medicine, C.U. Shah Medical College and Hospital, Surendranagar 363001, India

Keywords:

Cardiac glycoside, Arrhythmia, Congestive heart failure

Abstract

Digoxin is mainly used for heart failure and arrhythmias like atrial flutter and fibrillation. Digoxin is like double edged sword because of its potency to cause life threatening complications like various arrhythmias. Furthermore, it is difficult and important to recognize cardio toxicity caused by digoxin to prevent threat to life. We report a case which was initially diagnosed as arrhythmia and later turned as digoxin toxicity.

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References

Hollman A. Digoxin comes from Digitalis lanata. BMJ. 1996; 312:912.

Tripathi KD. Cardiac glycosides and drugs for heart failure. Essentials of medical pharmacology. 6th ed. New Delhi: Jaypee Brothers; 2009:493-507.

Zand F, Asadi S, Katibeh P. Good Outcome after Digoxin Toxicity Despite Very High Serum Potassium Level. Iran Red Crescent Med J 2011; 13: 680-1.

Doering W, Konig E, Sturm W. Digitalis intoxication: specifity and significance of cardiac and extracardiac symptoms. part I: Patients with digitalis-induced arrhythmias. Z Kardiol 1977; 66: 121-8.

The Uppsala monitoring centre. The use of WHO-UMC system for standardised case causality assessment. Available at http://www.who-umc.org. Accessed 1 August 2012.

Yang EH, Shah S, Criley JM. Digitalis toxicity: a fading but crucial complication to recognize. Am J Med 2012; 125:337-43.

Maron BA, Rocco TP. Pharmacotherapy of congestive heart failure. In: Bruton LS, editor. Goodman & Gillman’s The Pharmacological basis of Therapeutics. 12th ed. USA: Mc Graw Hill publication; 2011:789-813.

Lexi-Comp Online™ Interaction Lookup, 2010. Available at http://www.uptodate.com/crlsql/interact/frameset.jsp. Accessed 1 August 2012.

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Published

2017-02-03

How to Cite

Acharya, T. A., Mehta, D. S., & Vekariya, R. S. (2017). Digoxin toxicity: crucial to diagnose. International Journal of Basic & Clinical Pharmacology, 1(1), 39–40. Retrieved from https://www.ijbcp.com/index.php/ijbcp/article/view/1394

Issue

Section

Case Reports