Oral contraceptives induced hepatotoxicity


  • B. Akshaya Srikanth Clinical Pharmacist, Rajiv Gandhi Institute of Medical Sciences, Kadapa, Andhra Pradesh, India
  • V. Manisree Department of Obstetrics and Gynecology, Rajiv Gandhi Institute of Medical Sciences, Kadapa, Andhra Pradesh, India


Oral contraceptives, Hepatotoxicity, Drug toxicity, Combined oral contraceptive pills, hepatic carcinoma, India


Oral Contraceptives are the pharmacological agents used to prevent pregnancy. These are divided as the combined and progestogen methods and are administered orally, transdermally, systemically and via vaginal route. All these methods contain both oestrogen and progestogen. Vigorous usage of oral contraceptives and anabolic steroids as associated with cholestasis, vascular lesions and hepatic neoplasm. Benign hepatic neoplasms are clearly associated with oral contraceptives. In this article we discuss the various hepatocellular complications like cholestasis, benign neoplasm and hepatocellular carcinoma occurred by oral contraceptives.


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How to Cite

Srikanth, B. A., & Manisree, V. (2017). Oral contraceptives induced hepatotoxicity. International Journal of Basic & Clinical Pharmacology, 2(1), 91–93. Retrieved from https://www.ijbcp.com/index.php/ijbcp/article/view/1219



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