DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20183925

A retrospective study of prescription pattern of drugs in the management of stroke, at BRIMS teaching hospital, Bidar, India

Swetha K., Shailander Singh

Abstract


ABSTRACT

Background: Stroke is a leading cause of death worldwide these days. It is one of the major public health challenges, not only for neuropharmacology but the society in general. This study was conducted mainly to assess the prescribing pattern of drugs in stroke patients.

Methods: A retrospective study was conducted in the department of medicine at BRIMS teaching hospital over a period of 3 months. 40 Patients were included in this study based on the inclusion and exclusion criteria. Pharmacological therapy prescribed was analysed to determine the pattern of prescription of drugs.

Results: The incidence of stroke was higher in males as compared to females. Hypertension, smoking, and alcoholism were found to be the major risk factors for stroke. The major co-morbidities identified were hypertension and diabetes mellitus. In study of 40 patients 78% were identified as Ischemic stroke patients and 22% suffered Hemorrhagic stroke. The current prescribing trends were antihypertensive (35%), followed by antiplatelets (25%), statins (10%), antidiabetics (10%), antibiotics (11%) and nootropics (5%).

Conclusions: In order to promote the quality use of drugs, the prescribing pattern of drugs should be based on severity of stroke, associated co‑morbid conditions, and currently available evidences.


Keywords


Co-morbidities, Hypertension, Prescribing trend, Stroke

Full Text:

PDF

References


Preethi BP, Naveed AS, Sri Lakshmi G, Rao V. Prescribing pattern of drugs in stroke patients admitted to a multi-specialty hospital, India. Indo Am J Pharmaceut Res.2014;4(2):1015-20.

Singh H, Gupta JB, Gupta MS, Aggarwal R. Assessment of utility of Siriraj Stroke Score (SSS) in stroke patients of Pt. BD Sharma PGIMS hospital, Rohtak, India. Med J Indonesia. 2001 Aug 1;10(3):164-8.

Tapas K, Shyamal KD. Epidemiology of stroke in India. Neurol Asia. 2006;11(1):1-4.

Ovbiagele B, Nguyen-Huynh MN. Stroke epidemiology: advancing our understanding of disease mechanism and therapy. Neurotherapeut. 2011 Jul 1;8(3):319.

Po HL, Lin YJ, Hseuh IH. The prescribing patterns of antithrombotic agents for prevention of recurrent ischemic stroke. Acta Neurol Taiwan. 2009;18:98-103.

Ansari AK, Akhund IA, Shaikh AQ. Stroke in elderly; identification of risk factors. J Ayub Med Coll Abbottabad. 2001;13(3):11-3.

Ali L, Jameel H and Shah MA. Risk factors in stroke. J Coll Physicians Surg Pak. 1997;7:7-10.

Eapen RP and Parikh JP. A study of clinical profile and risk factors of cerebrovascular stroke. GMJ. 2009;64(2):47-54.

Kanji S, Corman C, Douen AG. Blood pressure management in acute stroke: comparison of current guidelines with prescribing patterns. Canadian J Neurolog Sci. 2002 May 1;29(2):125-31.

Vurumadla S, Rakshith V, Murari CH, Venkateshwarlu K. A study on symptoms, risk factors and prescribing pattern of drugs used in stroke patients. Int J Pharm Pharm Sci. 2015;7(1):421-6.

Abbasi MY, Ali MA. Prescribing pattern of drugs in stroke patients: A prospective study. Arch Pharma Practice. 2012 Oct 1;3(4):283.

Celin AT, Seuma J, Ramesh A. Assessment of drug related problems in stroke patients admitted to a South Indian tertiary care teaching hospital. Indian J Pharm Pract. 2012 Oct;5(4):28-33.

Lavy S, Melamed E, Cahane E, Carmon A. Hypertension and diabetes as risk factors in stroke patients. Stroke. 1973 Sep;4(5):751-9.